Key concepts to grasp

• No See'M Technology
• Reverse transcription
• Gain-of-function research
• Plausible deniability

Academic Papers

Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19

May 10, 2021, by Stephanie Seneff (Senior Research Scientist at the MIT) and Greg Nigh (Naturopathic Oncology)

42-page paper from the International Journal of Vaccine Theory, Practice, and Research 2(1)

Includes 188 citations and not too much technical jargon

Highlights:

• A possible link to prion diseases and neurodegeneration
• Spike proteins and blood disorders, neurodegenerative diseases and autoimmune diseases
• The potential for spike protein "shedding", transmission of the protein from a vaccinated to an unvaccinated person, resulting in symptoms induced in the latter.
• Modification of the DNA of those receiving the vaccination.

"The classic model of DNA → RNA → protein is now known to be false. It is now indisputable that there is a large class of viruses called retroviruses that carry genes that reverse transcribe RNA back into complementary DNA (cDNA). In 1975, Howard Temin, Renato Dulbecco, and David Baltimore shared the Nobel Prize in Physiology or Medicine in 1975 for their discovery of reverse transcriptase and its synthesis by retroviruses (such as human immunodeficiency virus (HIV)) to derive DNA from RNA (Temin and Mizutani, 1970, Baltimore, 1970). Much later, it was discovered that reverse transcriptase is not unique to retroviruses. More than a third of the human genome is devoted to mysterious mobile DNA elements called SINEs and LINEs (short and long interspersed nuclear elements, respectively). LINEs provide reverse transcriptase capabilities to convert RNA into DNA, and SINEs provide support for integrating the DNA into the genome. Thus, these elements provide the tools needed to convert RNA into DNA and incorporate it into the genome so as to maintain the new gene through future generations (Weiner, 2002)."

Unusual Features of the SARS-CoV-2 Genome Suggesting Sophisticated Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route

(aka The Yan Report, by Yan Limeng, September 2020

"Here we show that genetic evidence within the spike gene of SARS-CoV-2 genome (restriction sites flanking the RBM; tandem rare codons used at the inserted furin-cleavage site) does exist and suggests that the SARS-CoV-2 genome should be a product of genetic manipulation. Furthermore, the proven concepts, well-established techniques, and knowledge and expertise are all in place for the convenient creation of this novel coronavirus in a short period of time."

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome

December 2020, original version by Liguo Zhang and researchers from Harvard and MIT

"Prolonged SARS-CoV-2 RNA shedding and recurrence of PCR-positive tests have been widely reported in patients after recovery, yet these patients most commonly are non-infectious. Here we investigated the possibility that SARS-CoV-2 RNAs can be reverse-transcribed and integrated into the human genome and that transcription of the integrated sequences might account for PCR-positive tests. In support of this hypothesis, we found chimeric transcripts consisting of viral fused to cellular sequences in published data sets of SARS-CoV-2 infected cultured cells and primary cells of patients, consistent with the transcription of viral sequences integrated into the genome. To experimentally corroborate the possibility of viral retro-integration, we describe evidence that SARS-CoV-2 RNAs can be reverse transcribed in human cells by reverse transcriptase (RT) from LINE-1 elements or by HIV-1 RT, and that these DNA sequences can be integrated into the cell genome and subsequently be transcribed. Human endogenous LINE-1 expression was induced upon SARS-CoV-2 infection or by cytokine exposure in cultured cells, suggesting a molecular mechanism for SARS-CoV-2 retro-integration in patients. This novel feature of SARS-CoV-2 infection may explain why patients can continue to produce viral RNA after recovery and suggests a new aspect of RNA virus replication."

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

May 2021, modified / peer-reviewed version

An unresolved issue of SARS-CoV-2 disease is that patients often remain positive for viral RNA as detected by PCR many weeks after the initial infection in the absence of evidence for viral replication. We show here that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of the infected cell and be expressed as chimeric transcripts fusing viral with cellular sequences. Importantly, such chimeric transcripts are detected in patient-derived tissues. Our data suggest that, in some patient tissues, the majority of all viral transcripts are derived from integrated sequences. Our data provide an insight into the consequence of SARS-CoV-2 infections that may help to explain why patients can continue to produce viral RNA after recovery.

Wuhan COVID-19 Synthetic Origins and Evolution

March 2020, by Jean-Claude PEREZ with assistance from 2008 Nobel Laureate, Luc Antoine Montagnier

"Evidence of A Kind of 'Intelligent Will'

Figure 49: Is COVID-19 partially a "SYNTHETIC GENOME"
Figure 50:Evidence of 6 HIV/SIV cuntiguous inserts within a small COVID-19 region
Both figures proves evidence that the 6 HIV/SIV inserts are not the result of natural evolution and mutations. Particularly,

• Firstly, the 6 inserts are highlycontiguous: 169bp within 275bp regions.
• Secondly, HIV/SIV inserted strains are very homogeneous: Russia, Cote d'ivoire, Netherlands, Malawiorigins.
• Thirdly, the functions of inserts are also various: 2 from POL/RT, 4 from ENVELOPPE functional genes.
  Not reported in this article, wz found also within the COVID-19 genome 3 others HIV/SIV regions:one from ENVELOPPE, one from RT, and one from INTEGRASE.

POL/RT, INTEGRASE, and ENVELOPPE: we have here 3 majors functional pieces of genes necessary to build a retrovirus...

All this is remarkable and bears the mark of a desire for organization of a human nature: LOGIC, SYMETRIES!!!!!"

Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag

January 2020, by Prashant Pradhan et al. (This paper is still available, but it was "withdrawn" from official publication due to political pressure.)

"We found 4 insertions in the spike glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses. Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV-1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus."

Systematic Assembly and Genetic Manipulation of the Mouse Hepatitis Virus A59 Genome

Eric F. Donaldson, Amy C. Sims, and Ralph S. Baric, 2008

"We have developed a DNA assembly platform that utilizes the nonspecific, highly variable sequence signatures of type IIs restriction enzymes to assemble a full-length molecular clone of murine hepatitis coronavirus (MHV) strain A59. The approach also allows changes to be engineered into a DNA fragment by designing primers that incorporate the restriction site and the mutations of interest. By adding the type IIs restriction site in the proper orientation, subsequent digestion removes the restriction site and leaves a sticky end comprising the mutation of interest ready to ligate to a second fragment generated in parallel as its complement. In this chapter, we discuss the details of the method to assemble a full-length infectious clone of MHV and then engineer a specific mutation into the clone to demonstrate the power of this unique site-directed "No See'm" mutagenesis approach."

This 2008 (pre-COVID) paper is not explicitly related to SARS-CoV-2 or COVID-19, but it explains why most scientists and doctors wrongly believe and/or state that SARS-CoV-2 is a naturally-occurting virus. The No See-M bioweapon engineering approach is very clever, but not 100% foolproof, as indicated by the papers above. This 2008 paper reveals how to engineer a virus without leaving fingerprints, i.e., develop a bioweapon that appear to be naturally occurring.

Under the guise of "gain-of-function research" with multiple layers of comand and control, this technique has also provided a means for plausible deniability for the superiors of hundreds or thousands of researchers in academia, the pharmaceutical industry and military.

The No See’M mutagenesis approach is not only useful in assembling viruses with gain of function, but also derivative variants!

This way, bioweapons developers can first run tests and simulations on computers to plan viruses' degree of transmissablity and degree of virulence for targeted known genetic sequences either as one-time directed bioweapons or as latent pathogens that can become bioweapons at a later date when combined with a binary agent that is released either through injection or through an airborne bioweapon. Quantum computers can further speed up the process.

HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap

Veronique Zennou, Caroline Petit, Denise Guetard, Ulf Nerhbass, Luc Montagnier, and Pierre Charneau, April 2000

"HIV-1 and other lentiviruses have the unique property among retroviruses to replicate in nondividing cells. This property relies on the use of a nuclear import pathway enabling the viral DNA to cross the nuclear membrane of the host cell. In HIV-1 reverse transcription, a central strand displacement event consecutive to central initiation and termination of plus strand synthesis creates a plus strand overlap: the central DNA flap. We show here that the central DNA flap acts as a cis-determinant of HIV-1 DNA nuclear import. Wild-type viral linear DNA is almost entirely imported into the nucleus where it integrates or circularizes. In contrast, mutant viral DNA, which lacks the DNA flap, accumulates in infected cells as unintegrated linear DNA, at the vicinity of the nuclear membrane. Consistently, HIV-1 vectors devoid of DNA flap exhibit a strong defect of nuclear import, which can be corrected to wild-type levels by reinsertion of the DNA flap sequence."

This 2000 (pre-COVID) paper is not explicitly related to SARS-CoV-2 or COVID-19, but it explains how reverse transcription works and shows that scientists have known for many years that viruses can indeed permanently alter a host's DNA if they include HIV-1 inserts.

Videos

Dr. Peter McCullough MD Blows lid of Vaccine Dangers, May 2021

Dr. Peter McCullough began to give COVID vaccines to his patients in early 2021, but he stopped when he saw the effects. He said, "This whole pandemic from the beginning was about the vaccine! All roads lead to the vaccine … There are people who are stakeholders who do want a needle in every arm. Why? … The Wuhan spike protein – that’s extinct. People are getting vaccinated for something that doesn’t even exist any more… It’s a horrendous bioweapon that’s been thrust on the public."

5 Doctors Agree that COVID-19 Injections are Bioweapons and Discuss What to do About It

Dozens of Doctors Warn Against COVID-19 Vaccines

These men and women are very brave! They are risking their professional careers (and maybe their lives) to warn people of the dangers of these new types of vaccines. God bless these men and women!

Here are some of the most important quotes:

Dr. Ralf ER Sundberg (Sweden): The PCR test is inaccurate. It acutally causes so many false positives, so we are scared to vaccination, and I don't trust this vaccine.

Dr. Johan Denis (Belgium): The corona vaccine is not proven safe and effective. There is no medical emergency. It is a fake pandemic. It was all orchestrated to make you fearful enough to make you take the vaccine. This vaccine has been developed too quickly. We have no idea what the long-term effects will be. It needs much more investigation. There is no hurry or emergency. It might possibly change your DNA. This is irreversible and irrepairable for ALL future generations - an experiment on humanity. I would never give it to myself, my patients or my loved ones. We are no guinea pigs. There is nanotechnology present in this vaccine. Nanobots in hydrogels have bene developed for military purposes. There are strong indications it could make you a controllable puppet by means of your own smart phone connecte with a 5G network and artificial intelligence. In this way you could lose everything that makes you human. Very useful information can be found at https://childrenshealthdefense.org/.

Here are some of the other quotes:

Dr. Hilde De Smet (Belgium): I'd like to say that the new COVID-19 vaccine is not safe and that there is no global medical pandemic. For almost 20 years, the pharmaceutical industry has been trying to develop corona vaccines but never managed, because they saw in the animal trials that there were serious side effects - autoimmune disorders - when the animal was exposed to a new wild-type virus. These autoimmune disorders are comparable with the complications we have seen in some COVID-19 patients. Now, due to the excuse of a global pandemic, the Pharma industry has the permission to skip the animal trials. This means that we humans will be the guinea pigs, and we might get severe side effects when we are exposed to new viruses.

Dr. Vernon Coleman (UK): Doctors aren't allowed to question COVID-19 in public. Material containing the truth about the alleged disease and the vaccine is banned. In the last year, I've been demonized and lied about and a 50-year career and reputation trashed by those promoting a pandemic that never was and a vaccine that was never needed. The whole COVID-19 scam is as I've said in March 2020 the greatest hoax in history. The principle of informed consent is essentially missing, but patients now having vaccines can't give informed consent, because they aren't being informed. Thank heavens for sites such as BrandNewTube, which carry videos by doctors who've been censored or banned elsewhere.

Prof. Dolores Cahill (Ireland): The coronavirus and the lockdown was not as severe as was thought. We know that we can treat the symptoms of COVID-19 with vitamin D, C and Zinc and with very safe medicines. A vaccine is not necessary. There has never been a licensed RNA vaccine, and this is not because they have not had many clinical trials, but in the safety studies, there were significant adverse events and death in the animals that were used in these studies over the past 20 years.

Dr. Anna Forbes (UK): I'm a UK medical doctor here representing the UK Medical Freedom Alliance. We believe that there has been an overestimation of the public health risk from SARS COV-2 due to misrepresentation of data and inappropriate use of the PCR test. We call for the preservation of informed consent, medical choice and bodily autonomy. As doctors we believe it is absolutely crucial to maintain.

Dr. Anne Fierlafijn (Belgium): I think it's unacceptable that all liabilities have been waived for the companies that are producing it. If Pharma doesn't take responsibility for the product they make, how can they expect doctors to inject them to their patients without doubt of doing harm? The measures of corona cause more collateral damage than the virus itself.

This is only a few. The video has more. It is on Bitchute, because Google has been censoring YouTube videos.